Dr. Stephen Strange casts a forbidden spell that opens the doorway to the multiverse, including alternate versions of himself, whose threat to humanity is too great for the combined forces of Strange, Wong, and Wanda Maximoff.

Peter Parker, a.k.a. Spider-Man, is desperately trying to balance his dual identities. He can't keep up at college, pay his rent, or seem to make amends with his estranged best friend Harry and his beloved Mary Jane is more skeptical than ever. Peter begins to notice that he's losing some of his powers and wonders if the cost of being a superhero isn't too high. Meanwhile Peter's idol, the renowned scientist Otto Octavius, has turned into a maniacal...

Hoping to walk away with a massive fortune, a trio of thieves break into the house of a blind man who isn't as helpless as he seems.

Peter Parker is finally happy: he is doing well at the school, girlfriend MJ Watson loves him, and the whole city loves Spider-Man, finally bestowing upon him the praise he so rightly deserves. But peace may not be possible for a superhero. Harry Osborn has taken up his late father's mantle--becoming The New Goblin, bent on revenge. Uncle Ben's real killer, Flint Marko, has been transformed into the Sandman. An alien symbiote has attached itself to...